Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype
Francesca Tonelli, Silvia Cotti, Laura Leoni, Roberta Besio, Roberta Gioia, Loredana Marchese, Sofia Giorgetti, Simona Villani, Charlotte Gistelinck, Raimund Wagener, Birgit Kobbe, Imke A.K. Fiedler, Daria Larionova, Björn Busse, David R. Eyre, Antonio Rossi, P. Eckhard Witten, Antonella Forlino
Topics & Concepts
Osteogenesis imperfectaZebrafishPhenotypeCell biologyMedicinePathologyBiologyGeneticsGeneConnective tissue disorders researchProtease and Inhibitor MechanismsTGF-β signaling in diseases