KIF18b-dependent hypomethylation of PARPBP gene promoter enhances oxaliplatin resistance in colorectal cancer
Bing Hong, Ruyue Lü, Wanshuang Lou, Yuyan Bao, Lei Qiao, Yanyan Hu, Kaiping Liu, Jiaoe Chen, Dan-ni Bao, Ming Ye, Zejun Fang, Chaoju Gong, Xiaomin Zhang
Topics & Concepts
OxaliplatinColorectal cancerBiologyCancer researchDNMT3BGenePromoterDrug resistancePhenotypeMethylationMethyltransferaseCancerGene expressionGeneticsPARP inhibition in cancer therapyDNA Repair MechanismsMicrotubule and mitosis dynamics