Identification of 1,3,4-oxadiazolyl-containing β-carboline derivatives as novel α-glucosidase inhibitors with antidiabetic activity
Di Xiao, Li Lu, Bingwen Liang, Zhuang Xiong, Xue-Tao Xu, Wen‐Hua Chen
Topics & Concepts
AcarboseChemistryIC50EnzymeHydrogen bondDocking (animal)In vivoStereochemistryLead compoundBiochemistryPharmacologyIn vitroMoleculeOrganic chemistryBiologyNursingMedicineBiotechnologyNatural Antidiabetic Agents StudiesSynthesis and bioactivity of alkaloidsCholinesterase and Neurodegenerative Diseases