SAR1B senses leucine levels to regulate mTORC1 signalling
Jie Chen, Yuhui Ou, Rong Luo, Jie Wang, Dong Wang, Jialiang Guan, Yi Li, Peixue Xia, Peng R. Chen, Ying Liu
Topics & Concepts
mTORC1LeucineActivator (genetics)Gene silencingCell biologyAmino acidMechanistic target of rapamycinPI3K/AKT/mTOR pathwayBiologyIntracellularChemistrySignal transductionBiochemistryGenePI3K/AKT/mTOR signaling in cancerNeurobiology and Insect Physiology ResearchRNA and protein synthesis mechanisms