Litcius/Paper detail

Plexus-specific effect of flicker-light stimulation on the retinal microvasculature assessed with optical coherence tomography angiography

Martin Kallab, Nikolaus Hommer, Bingyao Tan, Martín Pfister, Andreas Schlatter, René M. Werkmeister, Jacqueline Chua, Doreen Schmidl, Leopold Schmetterer, Gerhard Garhöfer

2020American Journal of Physiology-Heart and Circulatory Physiology28 citationsDOI

Abstract

We present vessel density alterations in response to flicker stimulation using optical coherence tomography angiography and identified the superficial capillary plexus as the layer with the most pronounced effect. This points out the physiological importance of the microvasculature in mediating functional hyperemia and suggests a fine-tuned plexus-specific mechanism to meet cellular metabolic demands.

Topics & Concepts

Optical coherence tomography angiographyPlexusFlickerRetinalStimulationOptical coherence tomographyMedicineAngiographyTomographyAnatomyOphthalmologyRadiologyInternal medicineComputer scienceOperating systemRetinal Diseases and TreatmentsRetinal and Macular SurgeryRetinal Imaging and Analysis