Recent Advances in the Prins Reaction
Efraím Reyes, Liher Prieto, Uxue Uria, Luisa Carrillo, José L. Vicário
Abstract
The Prins reaction is a very convenient synthetic platform for the preparation of oxygen-containing heterocyclic compounds, especially tetrahydropyrans and tetrahydrofurans. While this reaction has been extensively used by synthetic chemists since its discovery, the last years have witnessed impressive improvements in its performance and scope and especially in the development of new catalytic and enantioselective versions. This mini-review presents these recent advances through selected representative examples.
Topics & Concepts
Prins reactionScope (computer science)Enantioselective synthesisBiochemical engineeringComputer scienceChemistryNanotechnologyCatalysisOrganic chemistryEngineeringMaterials scienceProgramming languageSynthetic Organic Chemistry MethodsAsymmetric Synthesis and CatalysisChemical Synthesis and Reactions