Adverse effects of Alport syndrome-related Gly missense mutations on collagen type IV: Insights from molecular simulations and experiments
Jingjie Yeo, Yimin Qiu, Gang Seob Jung, Yong‐Wei Zhang, Markus J. Buehler, David L. Kaplan
Topics & Concepts
Missense mutationIntegrinAlport syndromeAmino acidMolecular biologyMutantBiologyMutationBiochemistryChemistryGeneticsGeneReceptorGlomerulonephritisKidneyCell Adhesion Molecules ResearchCollagen: Extraction and CharacterizationProtease and Inhibitor Mechanisms