Litcius/Paper detail

[BO<sub>2</sub>]<sup>−</sup> as a Synthon for the Generation of Boron‐Centered Carbamate and Carboxylate Isosteres

Anne‐Frédérique Pécharman, Michael S. Hill, Claire L. McMullin, Mary F. Mahon

2020Angewandte Chemie International Edition21 citationsDOIOpen Access PDF

Abstract

Abstract Oxoborane carbamate and carboxylate analogues result from the in situ trapping of [BO 2 ] − produced by elimination of 2,3‐dimethyl‐2‐butene from a pinacolatoboryl anion.

Topics & Concepts

SynthonCarboxylateBoronCarbamateChemistryStereochemistryMedicinal chemistryOrganic chemistryOrganoboron and organosilicon chemistryBoron Compounds in ChemistryCrystallography and molecular interactions