Improved osseointegration of strontium-modified titanium implants by regulating angiogenesis and macrophage polarization
Wei Lü, Chuan Zhou, Yang Ma, Jia Li, Jimin Jiang, Yanqi Chen, Lingqing Dong, Fuming He
Abstract
experimental results also showed early vascularized implant osseointegration of SLA-Sr with the type H vessel formation around the SLA-Sr implant. This study emphasized the synergistic role of Sr in the regulation of macrophage polarization and angiogenesis, and therefore depicted the therapeutic potential of SLA-Sr for rapidly vascularized osseointegration.
Topics & Concepts
OsseointegrationAngiogenesisUmbilical veinMacrophage polarizationChemistryCell biologyIn vivoImplantMacrophageBiomedical engineeringCancer researchBiologyIn vitroMedicineSurgeryBiochemistryBiotechnologyBone Tissue Engineering MaterialsBone and Dental Protein StudiesOrthopaedic implants and arthroplasty