Brain-targeted CRISPR/Cas9 nanomedicine for effective glioblastoma therapy
Weimin Ruan, Mingzhu Jiao, Sen Xu, Muhammad Ismail, Xuan Xie, Yang An, Haixing Guo, Rongjun Qian, Bingyang Shi, Meng Zheng
Topics & Concepts
CRISPRNanomedicineCas9GlioblastomaGenetic enhancementCancer researchRibonucleoproteinTargeted therapyBlood–brain barrierChemistryMedicineBiologyGeneNeuroscienceNanotechnologyCancerRNABiochemistryCentral nervous systemMaterials scienceNanoparticleInternal medicineAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringRNA Interference and Gene Delivery