Photoinduced elimination of senescent microglia cells<i>in vivo</i>by chiral gold nanoparticles
Zhuojia Xu, Aihua Qu, Hongyu Zhang, Weiwei Wang, Changlong Hao, Meiru Lu, Baimei Shi, Liguang Xu, Maozhong Sun, Chuanlai Xu, Hua Kuang
Abstract
after two months of treatment. Our findings suggest a potential strategy to selectively eliminate senescent cells using chiral nanomaterials and offer a promising strategy for alleviating PD.
Topics & Concepts
In vivoMicrogliaColloidal goldChemistryNanoparticleNanotechnologyBiophysicsMaterials scienceBiologyInflammationImmunologyBiotechnologyNeuroinflammation and Neurodegeneration MechanismsNanoplatforms for cancer theranosticsAnesthesia and Neurotoxicity Research