AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Dana M. Gwinn, David B. Shackelford, Daniel F. Egan, Maria M. Mihaylova, Annabelle Méry, Debbie S. Vasquez, Benjamin E. Turk, Reuben J. Shaw
Topics & Concepts
AMPKmTORC1BiologyCell biologyPhosphorylationPI3K/AKT/mTOR pathwayAMP-activated protein kinaseEffectorMechanistic target of rapamycinSerineSignal transductionProtein kinase A14-3-3 protein interactionsPI3K/AKT/mTOR signaling in cancerMicrotubule and mitosis dynamics