Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-β/Smad signaling
Chaojie Chen, Jiajun Chen, Ying Wang, Liu Fang, Cuiling Guo, Tingting Sang, Peng He, Qian Zhao, Shengjia Chen, Xiaojian Lin, Xingya Wang
Topics & Concepts
Hepatic stellate cellSMADSignal transductionFibrosisInflammationApoptosisCancer researchBiologyChemistryCell biologyMolecular biologyImmunologyPathologyBiochemistryEndocrinologyMedicineFungal Biology and ApplicationsLiver physiology and pathologyPolysaccharides and Plant Cell Walls