Modulating the gut–liver axis and the pivotal role of the faecal microbiome in cirrhosis
Charlotte Woodhouse, Arjuna Singanayagam, Vishal Patel
Abstract
Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.
Topics & Concepts
CirrhosisMedicineDysbiosisGut microbiomeMicrobiomeGut floraIntestinal MicrobiomeLiver diseaseDiseaseGastroenterologyImmunologyBioinformaticsPathologyBiologyLiver Disease Diagnosis and TreatmentLiver Disease and TransplantationGut microbiota and health