LncRNA LINC-PINT increases SOCS1 expression by sponging miR-155-5p to inhibit the activation of ERK signaling pathway in rheumatoid arthritis synovial fibroblasts induced by TNF-α
Jing Wang, Qing Zhao
Topics & Concepts
Downregulation and upregulationMAPK/ERK pathwayGene silencingSignal transductionmiR-155BiologyCancer researchTumor necrosis factor alphaCell growthSmall interfering RNASynovial membraneCell biologyArthritisImmunologyCell cultureGeneTransfectionGeneticsCancer-related molecular mechanisms researchRNA Research and Splicinginterferon and immune responses