PI3K/Akt signaling in urological cancers: Tumorigenesis function, therapeutic potential, and therapy response regulation
Sahar Rezaei, Negin Nikpanjeh, Aryan Rezaee, Sarah Gholami, Reza Hashemipour, Negin Biavarz, Farnaz Yousefi, Ali Tashakori, Farshid Salmani, Romina Rajabi, Ramin Khorrami, Noushin Nabavi, Jun Ren, Shokooh Salimimoghadam, Mohsen Rashidi, Mohammad Arad Zandieh, Kiavash Hushmandi, Yuzhuo Wang
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BPTENCancer researchMedicineProstate cancerCarcinogenesisMetastasisCancerOncologyInternal medicineSignal transductionBiologyBiochemistryCancer-related gene regulationProtein Degradation and InhibitorsUbiquitin and proteasome pathways