Litcius/Paper detail

Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture

Yan-Ruide Li, Kuangyi Zhou, Derek Lee, Yichen Zhu, Tyler Halladay, Jiaji Yu, Yang Zhou, Zibai Lyu, Ying Fang, Yuning Chen, Sasha Semaan, Lili Yang

2025Nature Protocols25 citationsDOI

Topics & Concepts

Genetically engineeredGenetically modified organismImmunotherapyBiologyCancer immunotherapySynthetic biologyCell cultureNatural killer T cellCell biologyImmunologyComputational biologyGeneImmune systemGeneticsT cellCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology