The CDK4/6 Inhibitor Palbociclib Induces Cell Senescence of High-grade Serous Ovarian Cancer Through Acetylation of p53
Cong Ye, Yan Cheng, Xiaohong Qian, Bo Zhong, Jinchun Ma, Hongling Guo
Topics & Concepts
PalbociclibCell cycleSenescenceBiologyCancer researchCell growthCellCell cycle checkpointCancerMolecular biologyCell biologyBiochemistryGeneticsBreast cancerMetastatic breast cancerAdvanced Breast Cancer TherapiesCancer-related Molecular PathwaysPARP inhibition in cancer therapy