Synthesis of pH-responsive cyclometalated iridium(<scp>iii</scp>) complex and its application in the selective killing of cancerous cells
Peng Yang, Shaoqing Zhang, Ke Wang, Honglan Qi
Abstract
The pH-responsive cyclometalated iridium( iii ) complex [(3-pba) 2 Ir(1-Py-βC)]PF 6 was synthesized as an effective photosensitizer for the selective killing of cancerous cells.
Topics & Concepts
IridiumPhototoxicityChemistryLigand (biochemistry)Photodynamic therapyPhotoluminescenceQuantum yieldSelectivityBenzaldehydePhotochemistryCombinatorial chemistryFluorescenceIn vitroBiochemistryMaterials scienceReceptorCatalysisOrganic chemistryOptoelectronicsPhysicsQuantum mechanicsAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies