Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis
Shuai Shao, Chengjuan Chen, Gaona Shi, Yu Zhou, Yazi Wei, Ningyu Fan, Yan Yang, Lei Wu, Tiantai Zhang
Topics & Concepts
InflammasomePyrin domainExperimental autoimmune encephalomyelitisAIM2Multiple sclerosisPattern recognition receptorSignal transducing adaptor proteinCaspase 1ImmunologyBiologyImmune systemSecretionReceptorEncephalomyelitisNeuroinflammationInnate immune systemInflammationCell biologySignal transductionBiochemistryInflammasome and immune disordersSphingolipid Metabolism and Signalinginterferon and immune responses