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Kikuchi-Fujimoto Disease Following COVID-19

Hussain A Al Ghadeer, Sajjad M AlKadhem, Mohammed Sulaiman Almajed, Hassan M AlAmer, Jaber A Alhabeeb, Suad H Alomran, Abdullah S AlMajed

2022Cureus24 citationsDOIOpen Access PDF

Abstract

Kikuchi-Fujimoto Disease (KFD) is a rare self-limiting condition of unknown etiology. It is characterized by fever, and lymphadenopathy most commonly involving posterior cervical lymph nodes. Although it is of uncertain etiology, it is associated with viral infections and autoimmune diseases. Distinction from lymphadenopathy-associated alternate disorders is crucial to avoid unneeded diagnostic procedures and treatment. KFD is diagnosed based on histopathologic examination of the excised lymph node. The management is supportive with favorable outcomes within a few weeks or months. In this case, we describe a 13-year-old boy who complained of painful cervical lymphadenopathy and fever for more than three weeks following COVID-19. Diagnostic workup has been established and KFD diagnosis made based on the histopathologic features of the involved lymph node. The patient showed complete recovery with no recurrence during follow-up. So, this case highlights the possible association between COVID-19 and KFD during this pandemic and keeping it in the differential diagnosis.

Topics & Concepts

MedicineEtiologyCervical lymphadenopathyDifferential diagnosisDiseaseLymph nodeCervical lymph nodesLymphCoronavirus disease 2019 (COVID-19)Fever of unknown originDermatologyPathologySurgeryInternal medicineInfectious disease (medical specialty)CancerMetastasisLymphadenopathy Diagnosis and AnalysisSoft tissue tumors and treatmentTumors and Oncological Cases
Kikuchi-Fujimoto Disease Following COVID-19 | Litcius