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Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy

Lingling Xu, Engui Wang, Yong Kang, Dianxun Fu, Lin Luo, Yichang Quan, Xi Yuan, Jing‐Kai Huang, Xi Cui, Jia Zeng, Dongjie Jiang, Bojing Shi, Hongqing Feng, Han Ouyang, Chunying Chen, Zhou Li

2025Device14 citationsDOIOpen Access PDF

Abstract

Generating reliable high-voltage nanosecond pulses (hvNPs) is challenging in terms of materials, electronics, and power supply. Inspired by the natural phenomenon of lightning, we report a Schottky nanodiode array-enabled triboelectric nanosecond pulse generator (st-NPG) that eliminates the need for an external electrical power supply or boosting circuits, relying instead on mechanical energy input to directly generate hvNPs. This st-NPG, with high voltage (10 kV), peak power (17 MW), single-pulse energy (0.6 J), and stability (7 days of operation), is enabled by a capacitive wafer-scale semiconductor titanium dioxide (TiO 2 ) nanotube array with substantial charge storage and trapping capabilities. The st-NPG also enabled pulsed ablation for tumor treatment in mice and rabbits via minimally invasive interventional surgery. The ultracheap (<1/1,000 of commercial cost), power-source-free st-NPG should open opportunities for healthcare, environmental protection, science, and education applications around the world, especially in resource-poor regions.

Topics & Concepts

Triboelectric effectNanosecondMaterials scienceOptoelectronicsPulse (music)Pulse generatorGenerator (circuit theory)Electrical engineeringSchottky diodeNanotechnologyEngineeringOpticsVoltagePhysicsLaserDiodeComposite materialPower (physics)Quantum mechanicsAdvanced Sensor and Energy Harvesting MaterialsNeuroscience and Neural EngineeringAcoustic Wave Resonator Technologies
Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy | Litcius