Dual targeting of PD-L1 and PD-L2 by PCED1B-AS1 via sponging hsa-miR-194-5p induces immunosuppression in hepatocellular carcinoma
Fei Fan, Keji Chen, Xiaoliang Lü, Aijun Li, Caifeng Liu, Bin Wu
Topics & Concepts
Gene knockdownHepatocellular carcinomaCancer researchImmunosuppressionPD-L1In vitroCell culturemicroRNAMicrovesiclesMedicineIn vivoBiologyImmunologyImmune systemImmunotherapyGeneGeneticsBiotechnologyBiochemistryCancer-related molecular mechanisms researchCancer Immunotherapy and BiomarkersMicroRNA in disease regulation