Soy protein compared with whey protein ameliorates insulin resistance by regulating lipid metabolism, AMPK/mTOR pathway and gut microbiota in high-fat diet-fed mice
Andong Ji, Wei Chen, Chang Liu, Tianyu Zhang, Runjia Shi, Xinqi Wang, Huina Xu, Duo Li
Abstract
was lower in the SPI groups than those in the WPI groups. In conclusion, soy protein was more effective than whey protein in preventing IR in HFD-fed mice by regulating lipid metabolism, the AMPK/mTOR pathway, and gut microbiota.
Topics & Concepts
Insulin resistanceGLUT4Internal medicineEndocrinologyAMPKSoy proteinProtein kinase BPI3K/AKT/mTOR pathwayP70-S6 Kinase 1Lipid metabolismChemistryInsulinBiologyFood scienceProtein kinase ABiochemistryMedicineSignal transductionKinaseDiet and metabolism studiesPhytoestrogen effects and researchDiet, Metabolism, and Disease