Planktonic and Biofilm-Derived Pseudomonas aeruginosa Outer Membrane Vesicles Facilitate Horizontal Gene Transfer of Plasmid DNA
Ella L. Johnston, Lauren Zavan, Natalie J. Bitto, Steve Petrovski, Andrew F. Hill, Maria Kaparakis‐Liaskos
Abstract
OMVs to facilitate the dissemination of antibiotic resistance genes, thereby enabling the survival of susceptible bacteria during antibiotic treatment. Investigating the roles of biofilm-derived BMVs may contribute to furthering our understanding of the role of BMVs in HGT and the spread of antibiotic resistance in the environment.
Topics & Concepts
BiofilmPseudomonas aeruginosaMicrobiologyBacteriaPlasmidHorizontal gene transferBiologyBacterial outer membraneTransformation (genetics)DNABacterial geneticsAntibiotic resistanceAntibioticsGeneEscherichia coliGeneticsGenomeBacterial Infections and VaccinesCystic Fibrosis Research AdvancesCerebrospinal fluid and hydrocephalus