Augmenting and directing long-range CRISPR-mediated activation in human cells
Y. Esther Tak, Joy E. Horng, Nicholas T. Perry, Hayley T. Schultz, Sowmya Iyer, Qiuming Yao, Luli S. Zou, Martin J. Aryee, Luca Pinello, J. Keith Joung
Topics & Concepts
EpigeneticsCRISPREnhancerPromoterBiologyGeneTranscription factorRegulation of gene expressionCas9Computational biologyGenome editingGeneticsGene expressionCRISPR and Genetic EngineeringVirus-based gene therapy researchAdvanced biosensing and bioanalysis techniques