ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
Hui Peng, Qi Guo, Ye Xiao, Tian Su, Tie‐Jian Jiang, Lijuan Guo, Min Wang
Abstract
was potentially involved in the pathogenesis of age-related bone loss through regulating cellular senescence and osteogenic differentiation, which provides some new insights to treat age-related bone loss.
Topics & Concepts
SenescenceWnt signaling pathwayCell biologyMesenchymal stem cellCellular senescenceChemistryBone marrowIn vitroSignal transductionBiologyPhenotypeGeneImmunologyBiochemistryWnt/β-catenin signaling in development and cancerBone and Dental Protein StudiesEpigenetics and DNA Methylation