The efficacy and safety of remimazolam tosylate versus propofol in patients undergoing colonoscopy: a multicentered, randomized, positive-controlled, phase III clinical trial.
Shaohui Chen, Jin Wang, Xiaohan Xu, Yuguang Huang, Shanfu Xue, Anshi Wu, Xiaoju Jin, Qiang Wang, Jianrui Lyu, Sheng Wang, Yujuan Li, Yonghao Yu, AI Deng-bin, Ailin Luo, Su Min, Lin Li, Xiaohua Zou, Jin Liu, Peilin Lv, Xiaoqin Chai, Xude Sun, Zhibin Zhao, Jiaqiang Zhang
Abstract
<0.001) were less frequent in remimazolam group compared with propofol group. In conclusion, remimazolam tosylate is non-inferior in sedation efficacy while safer than propofol in patients undergoing colonoscopy.
Topics & Concepts
MedicinePropofolSedationColonoscopyAnesthesiaAdverse effectRandomized controlled trialSurgeryInternal medicineColorectal cancerCancerAnesthesia and Sedative AgentsAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive Disorders