Evaluation of Triple-Negative Breast Cancer Early Detection via Mammography Screening and Outcomes in African American and White American Patients

Abstract

Population-based breast cancer mortality is 40% higher among African American women compared with white American women, 1 a disparity partly explained by 2-fold higher incidence of biologically aggressive triple-negative breast cancer (TNBC) in African American women. 2 Screening mammography improves breast cancer survival through early detection, but TNBC is more challenging to detect mammographically compared with non-TNBC. 3-6 The value of screening mammography in reducing disparities through early detection of the disproportionately high TNBC burden observed in African American women is therefore uncertain.

Topics & Concepts