Integrative single-cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer
Chi-Yun Wu, Billy T. Lau, Heon Seok Kim, Anuja Sathe, Susan M. Grimes, Hanlee P. Ji, Nancy R. Zhang
Topics & Concepts
BiologyChromatinGeneticsCopy-number variationLoss of heterozygosityCancerAlleleSomatic cellComputational biologyChromatin remodelingCancer researchGenomeDNAGeneCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsEpigenetics and DNA Methylation