A fibroblastic foci-targeting and hypoxia-cleavable delivery system of pirfenidone for the treatment of idiopathic pulmonary fibrosis
Ting Zhao, Bokai Gong, Shiqin Luo, Rongping Zhang, Ling Zhang, Yuan Huang, Huile Gao, Tao Gong, Tao Gong
Topics & Concepts
PirfenidoneIdiopathic pulmonary fibrosisPulmonary fibrosisFibronectinExtracellular matrixHypoxia (environmental)FibrosisBovine serum albuminDrug deliveryBleomycinIn vivoPathologyCancer researchLungMedicineChemistryImmunologyBiologyInternal medicineChemotherapyBiochemistryOrganic chemistryBiotechnologyOxygenInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisInhalation and Respiratory Drug DeliveryMedical Imaging and Pathology Studies