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DNA-modularized construction of bivalent ligands precisely regulates receptor binding and activation

Na Zhao, Wenwei Wu, Ying Wang, Kun Song, Gaoxian Chen, Yingzhi Chen, Ruowen Wang, Jianrong Xu, Kai Cui, Hongzhuan Chen, Weihong Tan, Jian Zhang, Zeyu Xiao

2023Chem12 citationsDOI

Topics & Concepts

PharmacophoreBivalent (engine)DNAComputational biologyAgonistChemistryAllosteric regulationCombinatorial chemistryStereochemistryReceptorBiophysicsBiologyBiochemistryOrganic chemistryMetalReceptor Mechanisms and SignalingAdvanced biosensing and bioanalysis techniquesChemical Synthesis and Analysis
DNA-modularized construction of bivalent ligands precisely regulates receptor binding and activation | Litcius