Litcius/Paper detail

Finding potent inhibitors against SARS-CoV-2 main protease through virtual screening, ADMET, and molecular dynamics simulation studies

Rajarshi Roy, Md Fulbabu Sk, Nisha Amarnath Jonniya, Sayan Poddar, Parimal Kar

2021Journal of Biomolecular Structure and Dynamics27 citationsDOIOpen Access PDF

Abstract

-ligand association. This new compound may have great potential as a lead molecule to develop a new antiviral drug to fight against COVID-19.Communicated by Ramaswamy H. Sarma.

Topics & Concepts

Virtual screeningMolecular dynamicsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ProteaseCoronavirus disease 2019 (COVID-19)Computational biologyMolecular diagnosticsVirologyChemistryBiologyMedicineBioinformaticsEnzymeBiochemistryInfectious disease (medical specialty)PathologyComputational chemistryDiseaseComputational Drug Discovery MethodsProtein Structure and Dynamicsthermodynamics and calorimetric analyses