E3 ubiquitin ligase FBXW7 enhances radiosensitivity of non-small cell lung cancer cells by inhibiting SOX9 regulation of CDKN1A through ubiquitination
Hongge Zhu, Xiuli Wang, Xin Zhou, Suqiong Lu, Guomin Gu, Chunling Liu
Topics & Concepts
RadiosensitivityUbiquitin ligaseCancer researchSOX9BiologyMG132RadioresistanceUbiquitinApoptosisMolecular biologyCell biologyChemistryTranscription factorProteasome inhibitorCell cultureProteasomeMedicineInternal medicineRadiation therapyGeneticsGeneUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysProtein Degradation and Inhibitors