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A heme-dependent enzyme forms the hydrazine in the antibiotic negamycin

Menghua Wang, Zi-Wang Wei, Katherine S. Ryan

2025Nature Chemical Biology15 citationsDOI

Topics & Concepts

HemeChemistryEnzymeAntibioticsBiochemistryHydrazine (antidepressant)StereochemistryCombinatorial chemistryMicrobiologyBiologyChemical Reactions and IsotopesAmino Acid Enzymes and MetabolismAntibiotic Resistance in Bacteria
A heme-dependent enzyme forms the hydrazine in the antibiotic negamycin | Litcius