Pristimerin synergizes with gemcitabine through abrogating Chk1/53BP1-mediated DNA repair in pancreatic cancer cells
Zhuangzhuang Jiang, Yang Zhao, Yang Zhao, Yanqing Liu, Tao Li
Topics & Concepts
GemcitabineCHEK1Pancreatic cancerCancer researchChemistryKinaseCancerApoptosisBiologyBiochemistryCell cycle checkpointCell cycleGeneticsCancer therapeutics and mechanismsNatural Compounds in Disease TreatmentDNA Repair Mechanisms