Targeted degradation of hexokinase 2 by a novel engineered bispecific chimeric liposome-based Nano-PROTACs for enhancing tumor chemotherapy
Linlin Gong, Shasha Li, Jiahui Sun, Runjie Liu, Jianling Wang, Simeng Wang, Yuelei Zhao, Li Yan, Meiju Ji, Dan Yang, Peng Hou, Dechun Liu
Topics & Concepts
Materials scienceLiposomeNanotechnologyCancer researchMedicineProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways