Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol
Jing Wang, Sen Liu, Jiahuan Luo, Shaogang Hou, Haixiang Song, Yongsheng Niu, Chuanxiang Zhang
Abstract
An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5-190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.
Topics & Concepts
AmperometryDetection limitStackingMetal-organic frameworkElectrical conductorElectrochemistryCatalysisMaterials scienceReproducibilityLinear rangeNanotechnologyChemistryChromatographyElectrodeOrganic chemistryComposite materialPhysical chemistryAdsorptionElectrochemical sensors and biosensorsElectrochemical Analysis and ApplicationsAnalytical Chemistry and Sensors