Current Methods for the Detection of Antibodies of Varicella-Zoster Virus: A Review
Dequan Pan, Wei Wang, Tong Cheng
Abstract
Infection with the varicella-zoster virus (VZV) causes chickenpox and shingles, which lead to significant morbidity and mortality globally. The detection of serum VZV-specific antibodies is important for the clinical diagnosis and sero-epidemiological research of VZV infection, and for assessing the effect of VZV vaccine immunization. Over recent decades, a variety of methods for VZV antibody detection have been developed. This review summarizes and compares the current methods for detecting VZV antibodies, and discussed future directions for this field.
Topics & Concepts
ShinglesChickenpoxVaricella zoster virusVirologyMedicineVirusAntibodyImmunologyImmunizationEpidemiologyInternal medicineHerpesvirus Infections and TreatmentsPoxvirus research and outbreaksAnimal Virus Infections Studies