Litcius/Paper detail

Immunomodulation in Children

Elvira Verduci, Jutta Köglmeier

2021Journal of Pediatric Gastroenterology and Nutrition13 citationsDOIOpen Access PDF

Abstract

ABSTRACT: Immune maturation and response to inflammation depend on good nutritional status. Protein and amino acid deficiencies can compromise innate and adaptive immune functions, particularly following injury or during illness. Dietary omega-3 long-chain fatty acids, prebiotics and micronutrients are beneficial to the immune system. A complex interplay exists between diet, microbiome, and epigenetic factors. The effect of single nutrients on immune function may hence be difficult to study. Well-designed intervention studies, investigating the effects of whole dietary pattern on the immune system, are needed.

Topics & Concepts

Immune systemMicronutrientMicrobiomeMedicineInflammationAcquired immune systemEpigeneticsImmunologyInnate immune systemBioinformaticsBiologyBiochemistryGenePathologyClinical Nutrition and GastroenterologyFatty Acid Research and HealthChild Nutrition and Water Access