Litcius/Paper detail

Novel approach of multi-targeted thiazoles and thiazolidenes toward anti-inflammatory and anticancer therapy—dual inhibition of COX-2 and 5-LOX enzymes

Jaismy Jacob P, S. L. Manju

2020Medicinal Chemistry Research21 citationsDOI

Topics & Concepts

ChemistryZileutonPharmacologyPharmacophoreArachidonate 5-lipoxygenaseCelecoxibEtoricoxibIn vivoCyclooxygenaseAnti-inflammatoryIC50ThiazolePotencyCarrageenanIn vitroEnzymeStereochemistryBiochemistryArachidonic acidMedicineOrganic chemistryBiotechnologyBiologyInflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis and Reactions of Organic Compounds
Novel approach of multi-targeted thiazoles and thiazolidenes toward anti-inflammatory and anticancer therapy—dual inhibition of COX-2 and 5-LOX enzymes | Litcius