A prospective for the role of two-pore channels in breast cancer cells
Liu Hengrui
Abstract
Breast cancer is one of the most common cancers and the second most frequent cause of cancer death among women worldwide. Recently, potential links between cancer and the calcium mobilizing messenger Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and its intracellular target Two-Pore Channels (TPCs) have been identified.
Topics & Concepts
Breast cancerCancerIntracellularCalciumSecond messenger systemChemistryMedicineCancer researchInternal medicineBiochemistryCalcium signaling and nucleotide metabolismIon Channels and ReceptorsIon channel regulation and function