SP1-mediated transcriptional activation of PTTG1 regulates the migration and phenotypic switching of aortic vascular smooth muscle cells in aortic dissection through MAPK signaling
Chuangjia Hu, Weixing Huang, Nianling Xiong, Xiaoqiang Liu
Topics & Concepts
Western blotVascular smooth musclePhenotypic switchingOsteopontinPlatelet-derived growth factor receptorChromatin immunoprecipitationCell growthBiologyMolecular biologyCell biologyPlatelet-derived growth factorCell migrationCellGene expressionGrowth factorImmunologyGenePromoterEndocrinologyBiochemistrySmooth muscleReceptorAortic Disease and Treatment ApproachesAortic aneurysm repair treatmentsConnective tissue disorders research