Non-invasive brain stimulation to modulate neural activity in Parkinson’s disease
Manuel Bange, Rick C. Helmich, Aparna Wagle Shukla, Günther Deuschl, Muthuraman Muthuraman
Abstract
Despite its potential to modulate brain and network activity, non-invasive brain stimulation is not yet clinically applied for treating Parkinson's disease. We here review recent findings that illustrate how various non-invasive stimulation techniques can modify pathological and compensatory activities. Due to unavoidable heterogeneities and low effect sizes of the reviewed studies, a deeper understanding of the mechanisms of action will be critical for refining clinical effectiveness and generating consistent results.
Topics & Concepts
Parkinson's diseaseDeep brain stimulationNeuroscienceBrain stimulationMedicineDiseaseStimulationNeural activityNeurologyPsychologyInternal medicineNeurological disorders and treatmentsTranscranial Magnetic Stimulation StudiesNeuroscience and Neural Engineering