Identification of an immune checkpoint gene signature that accurately predicts prognosis and immunotherapy response in endometrial carcinoma
Shaowen Li, Chunli Dong, Jiayan Chen, Xiaocui Gao, Xiuying Xie, Xin Zhang
Abstract
silencing increased the migration and invasiveness of EC cells by promoting epithelial-mesenchymal transition (EMT). Collectively, these findings reveal an immune checkpoint gene signature that accurately predicts survival outcomes and immunotherapeutic responses in EC patients.
Topics & Concepts
ImmunotherapySignature (topology)Endometrial cancerImmune systemIdentification (biology)Gene signatureOncologyCarcinomaMedicineCancer researchComplete responseInternal medicineGeneImmunologyBiologyCancerGene expressionGeneticsChemotherapyGeometryMathematicsBotanyCancer Immunotherapy and BiomarkersEndometrial and Cervical Cancer TreatmentsImmunotherapy and Immune Responses