A review: strategies to reduce infection in tantalum and its derivative applied to implants
Xiao Ge, Ti Li, Miao Yu, Hongguang Zhu, Qing Wang, Xiuting Bi, Tiantian Xi, Xiaoyan Wu, Yubin Gao
Abstract
Implant-associated infection is the main reasons for implant failure. Titanium and titanium alloy are currently the most widely used implant materials. However, they have limited antibacterial performance. Therefore, enhancing the antibacterial ability of implants by surface modification technology has become a trend of research. Tantalum is a potential implant coating material with good biological properties. With the development of surface modification technology, tantalum coating becomes more functional through improvement. In addition to improving osseointegration, its antibacterial performance has also become the focus of attention. In this review, we provide an overview of the latest strategies to improve tantalum antibacterial properties. We demonstrate the potential of the clinical application of tantalum in reducing implant infections by stressing its advantageous properties.