Shotgun: A Bayesian seamless phase I-II design to accelerate the development of targeted therapies and immunotherapy
Liyun Jiang, Ruobing Li, Fangrong Yan, Timothy A. Yap, Ying Yuan
Topics & Concepts
MedicineInterimTolerabilityCohortInterim analysisClinical trialDrug developmentClinical study designBayesian probabilityOncologyMedical physicsDrugInternal medicineArtificial intelligencePharmacologyAdverse effectComputer scienceHistoryArchaeologyStatistical Methods in Clinical TrialsOptimal Experimental Design MethodsComputational Drug Discovery Methods