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Species Distribution and Comparison between EUCAST and Gradient Concentration Strips Methods for Antifungal Susceptibility Testing of 112 <i>Aspergillus</i> Section <i>Nigri</i> Isolates

Bastien Carrara, Randolph H. Richards, Sébastien Imbert, Florent Morio, Milène Sasso, Noël Zahr, Anne‐Cécile Normand, Patrice Le Pape, Laurence Lachaud, Stéphane Ranque, Danièle Maubon, Renaud Piarroux, Arnaud Fekkar

2020Antimicrobial Agents and Chemotherapy28 citationsDOIOpen Access PDF

Abstract

Aspergillus niger , the third species responsible for invasive aspergillosis, has been considered as a homogeneous species until DNA-based identification uncovered many cryptic species. These species have been recently reclassified into the Aspergillus section Nigri . However, little is yet known among the section Nigri about the species distribution and the antifungal susceptibility pattern of each cryptic species. A total of 112 clinical isolates collected from 5 teaching hospitals in France and phenotypically identified as A. niger were analyzed.

Topics & Concepts

PosaconazoleAspergillus nigerAmphotericin BAspergillusBiologyItraconazoleVoriconazoleAspergillosisAntifungalMicrobiologyVeterinary medicineBotanyBiotechnologyMedicineAntifungal resistance and susceptibilityPlant Pathogens and Fungal DiseasesInfectious Diseases and Mycology