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β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice

Yanrou Gu, Lidan Gao, Jiamin He, Man Luo, Mei Hu, Yuxian Lin, Jianxin Li, Tongyao Hou, Jianmin Si, Yingcong Yu

2024Food & Function13 citationsDOIOpen Access PDF

Abstract

and notable differences in metabolic pathways related to choline metabolism in cancer. In summary, NMN supplementation can delay frailty in old age, aid healthy ageing, and delay gut ageing.

Topics & Concepts

AgeingNicotinamide mononucleotideLife spanSenescenceNicotinamidePremature agingLongevityFunction (biology)EndocrinologyBiologyInternal medicineMedicineGerontologyNAD+ kinaseCell biologyPhysiologyBiochemistryNicotinamide adenine dinucleotideEnzymeSirtuins and Resveratrol in MedicineAdipose Tissue and MetabolismNeuroinflammation and Neurodegeneration Mechanisms
β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice | Litcius