Mechanistic evaluation of a novel cyclohexenone derivative’s functionality against nociception and inflammation: An in-vitro, in-vivo and in-silico approach
Jawad Khan, Gowhar Ali, Umer Rashid, Rasool Khan, Muhammad Saeed Jan, Rahim Ullah, Sajjad Ahmad, Sumra Wajid Abbasi, Atif Ali Khan Khalil, Robert D. E. Sewell
Topics & Concepts
NociceptionPharmacologyIn vivoChemistryOpioidergicPregabalinOpioid(+)-NaloxoneAnesthesiaMedicineReceptorBiochemistryBiologyBiotechnologyBioactive Compounds and Antitumor AgentsPharmacological Effects of Natural CompoundsPain Mechanisms and Treatments